







| 2026 | Tội Phạm 101 | Angie |
| 2025 | Màn đêm luôn tới | Doreen |
| 2024 | Poolman | Susan Kerkovish |
| 2022 | Sharp Stick | Marilyn |
| 2021 | Thức Giấc | Dr. Murphy |
| Bí Mật Bên Kia Khung Cửa | Jane Russell 2 | |
| 2020 | Người Sở Hữu | Girder |
| 2019 | QT8: The First Eight | Self |
| Sid & Judy | Judy Garland (voice) | |
| 2018 | Cậu bé buôn thuốc | Alex Snyder |
| Vùng Hủy Diệt | Dr Ventress | |
| 2017 | LBJ | Lady Bird Johnson |
| Good Time | Corey Ellman | |
| Amityville: Quỷ Dữ Thức Tỉnh | Joan Walker | |
| 2016 | Morgan | Dr. Kathy Grieff |
| None of Them Are You: Crafting Anomalisa | Self | |
| 2015 | Anomalisa | Lisa Hesselman (voice) |
| Tám Mối Hận | Daisy Domergue | |
| Welcome to Me | Deb Moseley | |
| Alex of Venice | Maureen | |
| 2014 | Me | Kelly |
| Jake Squared | Sheryl | |
| Hateship Loveship | Chloe | |
| Open | Holly | |
| 2013 | Giết Người Yêu Dấu | Naomi Ginsberg |
| The Spectacular Now | Sara Keely | |
| The Moment | Lee | |
| 2010 | Greenberg | Beth (Beller's Party) |
| 2009 | Der Regisseur Uli Edel - Fakten und Fiktion | Self |
| 2008 | Synecdoche, New York | Maria |
| 2007 | Margot at the Wedding | Pauline |
| 2006 | The Making of 'Last Exit to Brooklyn' | — |
| 2005 | Rag Tale | Mary Josephine 'MJ' Morton |
| Easter Sunday | Mother | |
| Palindromes | 'Mark' Aviva | |
| Ngăn Cản Thần Chết | Dr. Beth Lorenson | |
| 2004 | Gã Thợ Máy | Stevie |
| Childstar | Suzanne | |
| 2003 | Vết Cắt | Pauline |
| Celebrity Naked Ambition | Self (archive footage) | |
| 2002 | Searching for Debra Winger | Self (uncredited) |
| Con Đường Diệt Vong | Annie Sullivan | |
| Hey Arnold! The Movie | Bridget (voice) | |
| Crossed Over | Karla Faye Tucker | |
| 2001 | Người Đàn Ông Vắng Mặt | Female Inmate (voice) (uncredited) |
| The Quickie | Lisa | |
| The Anniversary Party | Sally Nash Therrian | |
| 2000 | Skipped Parts | Lydia Callahan |
| The King Is Alive | Gina | |
| Frame by Frame: The Invisible Art of Production Designer Carol Spier | Self | |
| 1999 | Trò Chơi Quái Ác | Allegra Geller |
| 1998 | Thanks of a Grateful Nation | Teri Small |
| The Love Letter | Lizzie Whitcomb | |
| 1997 | Washington Square | Catherine Sloper |
| A Thousand Acres | Caroline Cook | |
| Cinema Cinema | Herself | |
| 1996 | Bastard Out of Carolina | Anney Boatwright |
| Kansas City | Blondie O'Hara | |
| 1995 | The First 100 Years: A Celebration of American Movies | Self |
| Georgia | Sadie Flood | |
| Dolores Claiborne | Selena St. George | |
| 1994 | Would You Kindly Direct Me to Hell?: The Infamous Dorothy Parker | Self |
| Mrs. Parker and the Vicious Circle | Dorothy Parker | |
| The Hudsucker Proxy | Amy Archer | |
| 1993 | Short Cuts | Lois Kaiser |
| Luck, Trust & Ketchup: Robert Altman in Carver Country | Self | |
| 1992 | Single White Female | Hedra 'Hedy' Carlson |
| The Prom | Lana | |
| 1991 | Rush | Kristen Cates |
| Crooked Hearts | Marriet Hoffman | |
| Bức Tường Lửa | Jennifer Vaitkus | |
| 1990 | Partners in Life | Blossom |
| Buried Alive | Joanna Goodman | |
| Miami Blues | Susie Waggoner | |
| 1989 | The Big Picture | Lydia Johnson |
| Last Exit to Brooklyn | Tralala | |
| 1988 | Heart of Midnight | Carol |
| 1987 | Under Cover | Tanille Laroux |
| Sister, Sister | Lucy Bonnard | |
| 1986 | Picnic | Madge Owens |
| The Men's Club | Teensy | |
| Kẻ Đón Đường | Nash | |
| 1985 | Flesh + Blood | Agnes |
| 1984 | Grandview, U.S.A. | Candy Webster |
| 1983 | Girls of the White Orchid | Carol Heath |
| Easy Money | Allison Capuletti | |
| Have You Ever Been Ashamed Of Your Parents? | Andrea Fairchild | |
| 1982 | The First Time | Bonnie Dillon |
| Fast Times at Ridgemont High | Stacy Hamilton | |
| Wrong Is Right | Young Girl | |
| 1981 | The Best Little Girl in the World | Casey Powell |
| The Killing of Randy Webster | Amy Wheeler | |
| I Think I'm Having A Baby | Laurie Mcintyre | |
| Eyes of a Stranger | Tracy Harris | |
| 1980 | Angel City | Kristy Teeter |
| 1978 | The Young Runaways | Heather |
| 1976 | Tod eines Fremden | Girl Playing with Ball (uncredited) |
| 2010 | Greenberg | Story |
| Greenberg | Producer | |
| 2001 | Người Đàn Ông Vắng Mặt | Thanks |
| The Anniversary Party | Director | |
| The Anniversary Party | Writer | |
| The Anniversary Party | Producer | |
| 2000 | 3 Kẻ Trốn Tù | Thanks |
| Skipped Parts | Co-Producer | |
| 1995 | Georgia | Producer |