| 2024 | Les Barbares | Joëlle |
| 2023 | The Lesson | Hélène Sinclair |
| Godard, seul le cinéma | Self |
| Godard, seul le cinéma | — |
| Daniel Brühl – Der Reiz des Bösen | Self - Actress |
| 2021 | Gadające głowy 2021 | Self |
| 2020 | Before the End | Self - Céline |
| 2019 | My Zoe | Isabelle Perrault |
| 2018 | Be Natural: The Untold Story of Alice Guy-Blaché | Self |
| Burning Shadow | Mrs. Looper |
| 2017 | Thị Trấn Tình Yêu | Carine Roussel |
| The Space in Between | Self |
| After Before | Self |
| 2016 | Richard Linklater: Dream Is Destiny | Self |
| Wiener-Dog | Dina |
| The 4%: Film's Gender Problem | Self |
| 2015 | Lolo | Violette |
| Avengers 2: Đế Chế Ultron | Madame B |
| 2014 | 21 Years: Richard Linklater | Self - Actress |
| 2013 | Cinéast(e)s | Self |
| Trước Lúc Nửa Đêm | Céline |
| 2012 | 2 Days in New York | Marion |
| 2011 | Le Skylab | Anna |
| 2009 | Nữ Bá Tước Khát Máu | Erzsébet Báthory |
| 2007 | Guilty Hearts | Charlotte |
| 2 Days in Paris | Marion |
| The Air I Breathe | Gina |
| 2006 | The Hoax | Nina Van Pallandt |
| Histoire(s) du cinéma 3b : une vague nouvelle | (archive footage) (uncredited) |
| Histoire(s) du cinéma 2b : fatale beauté | Self - Narrator (voice) |
| Histoire(s) du cinéma 2a : seul le cinéma | Girl |
| The Legend of Lucy Keyes | Jeanne Cooley |
| 2005 | Những Cánh Hoa Rơi | Sherry |
| Before Sunset: Behind the Scenes | — |
| 2004 | Linklater: St. Richard of Austin | Self |
| Trước Lúc Hoàng Hôn | Céline |
| 2002 | Looking for Jimmy | Al |
| Beginner's Luck | Anya |
| Intimate Affairs | Chloe |
| Villa Des Roses | Louise Creteur |
| 2001 | Đánh Thức Cuộc Đời | Celine |
| MacArthur Park | Wendy |
| 2000 | Sand | Lill |
| But I'm a Cheerleader | Lipstick Lesbian |
| 1999 | L.A. Without a Map | Julie |
| The Passion of Ayn Rand | Barbara Branden |
| 1998 | Crime and Punishment | Sonia Marmeladova |
| The Treat | Francesca |
| Peter Beard: Scrapbooks from Africa and Beyond | (voice) |
| 1997 | Bush: Alleys and Motorways | Self |
| Les mille merveilles de l'univers | Eva Purpur |
| An American Werewolf in Paris | Serafine Pigot |
| 1996 | Tykho Moon | Lena |
| 1995 | Trước Lúc Bình Minh | Céline |
| 1994 | Ba Sắc Màu: Đỏ | Dominique |
| Ba Sắc Màu: Trắng | Dominique |
| Sunny Side Up | Julie Delpy |
| 1993 | The Three Musketeers | Constance |
| Killing Zoe | Zoe |
| Younger and Younger | Melodie |
| Ba Sắc Màu: Xanh | Dominique |
| 1992 | Warszawa. Année 5703 | Fryda |
| 1991 | Homo Faber | Sabeth |
| 1990 | Europa Europa | Leni |
| 1989 | Histoire(s) du cinéma 1a : toutes les histoires | Self - Narrator (voice) |
| Histoire(s) du cinéma 1b : une histoire seule | Self - Narrator (voice) |
| La noche oscura | Virgen María |
| 1988 | L'Autre nuit | Marie |
| King Lear | Virginia |
| 1987 | La Passion Béatrice | Béatrice de Cortemart |
| 1986 | Mauvais Sang | Lise |
| Couple | Self |
| 1985 | L'Amour ou presque | Mélie |
| Détective | Wise Young Girl |
| 1984 | Cinématon XXXVIII | N°376 |
| 1978 | Cinématon | N°376 |
| Guerres civiles en France | (segment "La semaine sanglante") |