| 2026 | Ebenezer: A Christmas Carol | Ebenezer Scrooge |
| 2025 | Andrea Bocelli - The Celebration:30th Anniversary | — |
| Pirates of the Caribbean | Disneyland Resort | Captain Jack Sparrow (voice) |
| Caliu: Nicidecum altceva, ce să fac altceva? | Self |
| The Rock Prophet: The Story of Link Wray | Self |
| Chaplin: Espíritu gitano | Self |
| 2024 | The Private Lives of Jordi Molla' & Domingo Zapata | Johnny Depp |
| Scab Vendor: The Life and Times of Jonathan Shaw | Self |
| Tim Burton: Life in the Line | Self |
| Johnny Puff: Secret Mission | Johnny Puff (voice) |
| 2023 | Hollywood Vampires: Live In Rio | Guitars / Lead Vocals / Backing Vocals |
| Jeanne du Barry | Louis XV |
| Affaire Johnny Depp/Amber Heard - La justice à l'épreuve des réseaux sociaux | Self |
| 2022 | Savage X Fenty Show Vol. 4 | Self (uncredited) |
| Depp vs Heard: The Verdict | Self (archive footage) |
| TMZ Presents | Johnny vs. Amber: From Love to Hate | Self (archive footage) |
| Depp Vs. Heard: Winners & Losers | Self |
| Tell Me Iggy | Self |
| Winona Ryder - Die Geister, die sie rief | Self (archive footage) |
| Johnny Depp contro Amber Heard - Dall'amore al processo | Self (archive footage) |
| 2021 | I Am a Mutoid: A Glastonbury Hero | Self (Archive Footage) |
| Kрека: Ловац на снове | Self |
| kid 90 | Self (archive footage) |
| 2020 | Crock of Gold: A Few Rounds with Shane MacGowan | Self (archive footage) |
| Chờ Người Man Rợ | Colonel Joll |
| Thảm Họa Minamata | W. Eugene Smith |
| 2019 | The Professor | Richard Brown |
| Nice Girls Don't Stay for Breakfast | Self - Actor |
| 2018 | Sinh Vật Huyền Bí: Tội Ác của Grindelwald | Grindelwald |
| Brothers in Arms | Self |
| London Fields | Chick Purchase |
| Thành Phố Dối Trá | Russell Poole |
| Hollywood Vampires Live at Hellfest 2018 | Self |
| Sherlock Gnomes: Thám Tử Siêu Quậy | Sherlock Gnomes (voice) |
| 2017 | Án Mạng Trên Chuyến Tàu Tốc Hành Phương Đông | Edward Ratchett |
| Lunch Ladies | Self (uncredited) |
| Cướp Biển Vùng Caribbean: Salazar Báo Thù | Jack Sparrow |
| The Black Ghiandola | Nuclear Med Tech |
| 2016 | David Blaine: Beyond Magic | Self |
| Sinh Vật Huyền Bí và Nơi Tìm Ra Chúng | Gellert Grindelwald |
| Nữ Sinh Bắt Ma | Guy Lapointe |
| Alice Ở Xứ Sở Trong Gương | Tarrant Hightopp / Mad Hatter |
| Donald Trump's The Art of the Deal: The Movie | Donald J. Trump |
| 2015 | Liên Minh Đen | James 'Whitey' Bulger |
| The 90s: Ten Years That Changed the World | Self (archive footage) (uncredited) |
| The Nightmare | Self (archive footage) |
| Quý Tộc Săn Tranh | Charlie Mortdecai |
| 2014 | Khu Rừng Cổ Tích | Big Bad Wolf |
| Răng Nanh | Guy Lapointe |
| Don Rickles: One Night Only | Self |
| Trí Tuệ Siêu Việt | Dr. Will Caster |
| 2013 | Lucky Them | Matthew Smith |
| Kỵ Sĩ Cô Độc | Tonto |
| Don't Say No Until I Finish Talking: The Story of Richard D. Zanuck | Self |
| 2012 | Radioman | Self |
| Phía Tây Memphis | Self – WM3 Supporter |
| Paradise Lost 3: Purgatory | Self |
| For No Good Reason | Self |
| Dark Shadows: The Collinses - Every Family Has Its Demons | Self |
| Roman Polanski: A Film Memoir | Self (archive footage) |
| Close Up | Self (archive footage) |
| Lời Nguyền Bóng Đêm | Barnabas Collins |
| Sunset Strip | Self |
| Cớm Học Đường | Officer Tom Hanson (uncredited) |
| Кустурица - Балкански хулиган | Himself |
| 2011 | Jack and Jill | Johnny Depp (uncredited) |
| Pirates of the Caribbean: Tales of the Code: Wedlocked | Jack Sparrow (archive footage) |
| The Rum Diary | Paul Kemp |
| Real Creatures of Dirt | Self / Rango / Lars |
| Cướp Biển Vùng Caribbean: Suối Nguồn Tươi Trẻ | Jack Sparrow |
| Rango: Tắc Kè Bông | Rango / Lars (voice) |
| 2010 | Du Khách Bí Ẩn | Frank Tupelo |
| Alice in Wonderland: Finding Alice | Self |
| Alice in Wonderland: The Mad Hatter | Self |
| Alice in Wonderland: Effecting Wonderland | Self |
| When You're Strange | Narrator (voice) |
| Alice Ở Xứ Sở Thần Tiên | Tarrant Hightopp / Mad Hatter |
| 2009 | Ballybrando | Self (archive footage) |
| Michael Mann: Making 'Public Enemies' | Self |
| Đánh Cược Với Quỷ | Imaginarium Tony 1 |
| Kẻ Thù Quốc Gia | John Dillinger |
| SpongeBob vs. the Big One | Jack Kahuna Laguna (voice) |
| 2008 | Gonzo: The Life and Work of Dr. Hunter S. Thompson | Narrator (voice) |
| Rock and a Hard Place: Another Night at the Agora | Self |
| Sweeney Todd: The Demon Barber of Fleet Street - Burton + Carter + Depp = Todd | Self |
| 2007 | Sweeney Todd: Thợ Cắt Tóc Quỷ của Phố Fleet | Sweeney Todd |
| Voom Portraits | Self |
| Cướp Biển Vùng Caribbean: Nơi Tận Cùng Thế Giới | Jack Sparrow |
| Joe Strummer: The Future Is Unwritten | Self |
| Brando | Self |
| 2006 | Buy the Ticket, Take the Ride | Self |
| According to Plan: The Harrowing and True Story of Dead Man's Chest | Self |
| Cướp Biển Vùng Caribbean: Chiếc Rương Tử Thần | Jack Sparrow |
| Gypsy Caravan: When the Road Bends | Self |
| Deep Sea 3D | — |
| 2005 | Cô Dâu Ma | Victor Van Dort (voice) |
| Charlie và Nhà Máy Sôcôla | Willy Wonka |
| It Came from... Baltimore!! | Self |
| Nos Bastidores de Hollywood | Self (archive footage) |
| 2004 | Đi Tìm Miền Đất Hứa | Sir James Matthew Barrie |
| Ed Wood: Let's Shoot This @#!% | Self |
| Ed Wood: Making Bela | Self / Edward D. Wood Jr. (archive footage) |
| Ed Wood: Pie Plates Over Hollywood | Self (archive footage) |
| The Libertine | Rochester |
| Ils se marièrent et eurent beaucoup d'enfants | L'inconnu |
| Secret Window: From Book to Film | — |
| Secret Window: A Look Through It | — |
| The Buried Secret of M. Night Shyamalan | Self |
| Ô Cửa Bí Mật | Mort Rainey |
| 2003 | Mexico Một Thời Oanh Liệt | CIA Agent Jeffrey Sands |
| Cướp Biển Vùng Caribbean: Lời Nguyền Tàu Ngọc Trai Đen | Jack Sparrow |
| Breakfast with Hunter | Self |
| Charlie: The Life and Art of Charles Chaplin | — |
| Hunter Goes to Hollywood | Self |
| 2002 | All the Love You Cannes! | Self |
| Histoires de festival | Self (archive footage) |
| Lost in La Mancha | Self |
| 2001 | Một đời chìm đắm | George Jung |
| From Hell | Fred Abberline |
| A Tour of the Inferno: Revisiting 'Platoon' | Self |
| 2000 | Viên Kẹo Ngọt Ngào | Roux |
| Before Night Falls | Bon Bon / Lieutenant Victor |
| Nước Mắt Đàn Ông | Cesar |
| Sleepy Hollow: Behind the Legend | Self |
| 1999 | Kỵ Sỹ Không Đầu | Ichabod Crane |
| In Bad Taste | Self |
| Vợ Của Phi Hành Gia | Commander Spencer Armacost |
| Cánh Cổng Thứ Chín | Dean Corso |
| L.A. Without a Map | Self / William Blake (uncredited) |
| The Source | Jack Kerouac |
| 1998 | Spotlight on Location: Fear and Loathing in Las Vegas | Self |
| Run Sợ ở Las Vegas | Raoul Duke |
| 1997 | The Brave | Raphael |
| Kẻ Nằm Vùng | Donnie Brasco / Joseph D. 'Joe' Pistone |
| 1996 | Cannes Man | Self |
| 1995 | Dead Man | William Blake |
| Sinatra: 80 Years My Way | Self - Audience Member (uncredited) |
| Thời Khắc Quyết Định | Gene Watson |
| Help! War Child | Self |
| 1994 | Don Juan DeMarco | Don Juan DeMarco |
| Ed Wood | Ed Wood |
| 1993 | What's Eating Gilbert Grape | Gilbert Grape |
| Benny & Joon | Sam |
| Arizona Dream | Axel Blackmar |
| 1991 | Freddy's Dead: The Final Nightmare | Teen on TV |
| 1990 | The Making of Edward Scissorhands | Self |
| Người Kéo Học Yêu | Edward Scissorhands |
| Cry-Baby | Wade 'Cry-Baby' Walker |
| 1986 | Trung Đội | Gator Lerner |
| Slow Burn | Donnie Fleischer |
| R.P.G | Vinnie Dooler |
| 1985 | Private Resort | Jack |
| 1984 | Ác Mộng Phố Elm | Glen Lantz |